Neutrofilna kolagenaza

Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

Neutrofilna kolagenaza
Neutrofilna kolagenaza
Identifikatori
EC broj	3.4.24.34
CAS broj	2593923
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

Neutrofilna kolagenaza (EC 3.4.24.34, matrična metaloproteinaza 8, PMNL kolagenaza, MMP-8) je enzim.^[1]^[2]^[3] Ovaj enzim katalizuje sledeću hemijsku reakciju

Razlaganje intestinalnih kolagena u trostruko heliksnom domenu. Za raliku od EC 3.4.24.7, intestinalna kolagenaze, ovaj enzim razlaže tip III kolagena sporije nego tip I

Ovaj enzuim je sličan sa interstinalnom kolagenazom.

Reference

^ Hasty, K. (1987). „A., Jeffrey, J. J., Hibbs, M. S. and Welgus, H. G. The collagen substrate specificity of human neutrophil collagenase”. J. Biol. Chem. 262: 10048—10052. PMID 3038863.
^ Hasty, K. (1990). „A., Pourmotabbed, T. F., Goldberg, G. I., Thompson, J. P., Spinella, D. G., Stevens, R. M. and Mainardi, C. L. Human Neutrophil Collagenase. A distinct gene product with homology to other matrix metalloproteinases”. J. Biol. Chem. 265: 11421—11424. PMID 2164002.
^ Knäuper, V., Krämer, S., Reinke, H. and Tschesche, H. (1990). „Characterization and activation of procollagenase from human polymorphonuclear leucocytes. N-terminal sequence and determination of the proenzyme and various proteolytically activated forms”. Eur. J. Biochem. 189: 295—300. PMID 2159879.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.

Spoljašnje veze

Neutrophil+collagenase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Hasty, K. (1987). „A., Jeffrey, J. J., Hibbs, M. S. and Welgus, H. G. The collagen substrate specificity of human neutrophil collagenase”. J. Biol. Chem. 262: 10048—10052. PMID 3038863.

[2] Hasty, K. (1990). „A., Pourmotabbed, T. F., Goldberg, G. I., Thompson, J. P., Spinella, D. G., Stevens, R. M. and Mainardi, C. L. Human Neutrophil Collagenase. A distinct gene product with homology to other matrix metalloproteinases”. J. Biol. Chem. 265: 11421—11424. PMID 2164002.

[3] Knäuper, V., Krämer, S., Reinke, H. and Tschesche, H. (1990). „Characterization and activation of procollagenase from human polymorphonuclear leucocytes. N-terminal sequence and determination of the proenzyme and various proteolytically activated forms”. Eur. J. Biochem. 189: 295—300. PMID 2159879.

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