Sortaza-B

Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

Sortaza-B
Sortaza-B
Identifikatori
EC broj	3.4.22.71
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

Sortaza-B (EC 3.4.22.71, SrtB) je enzim.^[1]^[2] Ovaj enzim katalizuje sledeću hemijsku reakciju

Ovaj enzim katalizuje reakciju sortiranja ćelijskog zida u kojoj se površinski protein sa signalom sortiranja koji sadrži NXTN motif razlaže. Rezultujući treonin karboksilni kraj proteina je kovalentno veza za pentaglicin peptidoglikana.

Ovaj enzim pripada peptidaznoj familiji C60.

Reference

^ Zong, Y., Mazmanian, S.K., Schneewind, O. and Narayana, S.V. (2004). „The structure of sortase B, a cysteine transpeptidase that tethers surface protein to the Staphylococcus aureus cell wall”. Structure. 12: 105—112. PMID 14725770.
^ Bierne, H., Garandeau, C., Pucciarelli, M.G., Sabet, C., Newton, S., Garcia-del Portillo, F., Cossart, P. and Charbit, A. (2004). „Sortase B, a new class of sortase in Listeria monocytogenes”. J. Bacteriol. 186: 1972—1982. PMID 15028680.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.

Spoljašnje veze

Sortase+B на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Zong, Y., Mazmanian, S.K., Schneewind, O. and Narayana, S.V. (2004). „The structure of sortase B, a cysteine transpeptidase that tethers surface protein to the Staphylococcus aureus cell wall”. Structure. 12: 105—112. PMID 14725770.

[2] Bierne, H., Garandeau, C., Pucciarelli, M.G., Sabet, C., Newton, S., Garcia-del Portillo, F., Cossart, P. and Charbit, A. (2004). „Sortase B, a new class of sortase in Listeria monocytogenes”. J. Bacteriol. 186: 1972—1982. PMID 15028680.

[1]

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