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厄妥索单抗

厄妥索单抗
单克隆抗体
种类三功能抗体英语Trifunctional antibody
目標HER2/neu, CD3
臨床資料
商品名英语Drug nomenclatureRexomun
ATC碼
  • 未分配
识别信息
CAS号509077-99-0  ☒N
ChemSpider
  • none
UNII

厄妥索单抗INN:Ertumaxomab),或译厄马索单抗,商品名Rexomun,是一种三功能单克隆抗体,设计用于治疗乳癌腹膜癌病英语Peritoneal carcinomatosis[1][2]它通过将T淋巴细胞巨噬细胞癌细胞连接起来发挥作用。[3]

由于费森尤斯开发计划的改变,评估乳癌治疗的II期临床试验被终止。[4](以便他们可以专注于其他产品如卡妥索单抗英语catumaxomab(商品名Removab)。[5]:35

参考资料

  1. ^ Kiewe, Philipp; Thiel, Eckhard. Ertumaxomab: a trifunctional antibody for breast cancer treatment. Expert Opinion on Investigational Drugs. 2008-10, 17 (10) [2024-01-23]. ISSN 1744-7658. PMID 18808314. doi:10.1517/13543784.17.10.1553. (原始内容存档于2024-04-12). 
  2. ^ ASCO-Meeting: Fresenius Biotech presents clinical trial results of new antibodies at the world's largest cancer convention | FSE. www.fresenius.com. [2024-01-23]. (原始内容存档于2024-01-23) (英语). 
  3. ^ Ertumaxomab Overview - Creative Biolabs. www.creativebiolabs.net. [2024-01-23]. 
  4. ^ ClinicalTrials.gov: Phase II Study With the Trifunctional Antibody Ertumaxomab to Treat Metastatic Breast Cancer After Progression on Trastuzumab Therapy. [2024-01-23]. (原始内容存档于2016-04-10). 
  5. ^ 2009 Consolidated Financial Statements and Management Report of Fresenius SE (PDF). [2016-03-20]. (原始内容 (PDF)存档于2016-03-31). 
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