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希内斯·莫拉塔

希内斯·莫拉塔
ForMemRS
2017年7月
出生Ginés Morata Pérez
(1945-04-19) 1945年4月19日79歲)
 西班牙里奥哈
国籍 西班牙
母校马德里康普顿斯大学PhD
知名于发育生物学
奖项阿斯图里亚斯亲王奖(2007年)
科学生涯
研究领域生物学和遗传学
机构马德里自治大学
剑桥大学
论文《决定果蝇性状的遗传细胞》(1973年)
博士導師安东尼奥·加西亚-贝利多[1]
受影响自彼得·劳伦斯[2]

希内斯·莫拉塔·佩雷斯(西班牙語:Ginés Morata Pérez,1945年4月19日),西班牙生物学家,现任马德里自治大学研究教授[1]。他是专注研究果蝇发育生物学超过40年的专家[3][4]

经历

莫拉塔于1945年出生于阿尔梅里亚省里奥哈市。本科就读于塞维利亚劳动大学(现巴勃罗·德奥拉维德大学英语Pablo_de_Olavide_University),毕业后进入了马德里康普顿斯大学深造[5]。1973年,他在安东尼奥·加西亚-贝利多教授的指导下完成了毕业论文《决定果蝇性状的遗传细胞》[6],并获得了博士学位[7]

在取得博士学位之后,他在英国剑桥大学英國醫學研究委員會分子生物学实验室(LMB)工作了数年。他的同事包括彼得·劳伦斯[2][3]。1975年,他加入了西班牙国家研究委员会。1990年-1992年,他出任马德里自治大学分子生物学中心主任[5]

莫拉塔参与了许多生物学领域的突破性研究,包括细胞竞争现象、体节形成时前后区室英语Compartment (development)的分化现象[8]细胞凋亡时的丝裂原信号的发现,以及对同源异形基因的深入研究。截至2017年 (2017-Missing required parameter 1=month!),他的研究重点是细胞竞争[9][10]以及细胞凋亡癌变的关系[11][12][13]。这些研究有助于深入理解细胞再生机制,并为癌症防治研究指明新方向[5]

奖项和荣誉

荣誉称号

奖项

参考文献

  1. ^ 1.0 1.1 Morata, Ginés. Ginés Morata. Current Biology. 2006, 16 (23): R976–R977. ISSN 0960-9822. PMID 17195314. doi:10.1016/j.cub.2006.10.047. 
  2. ^ 2.0 2.1 Morata, G.; Lawrence, P. A. Control of compartment development by the engrailed gene in Drosophila. Nature. 1975, 255 (5510): 614–617. ISSN 0028-0836. doi:10.1038/255614a0.  付费文献
  3. ^ 3.0 3.1 3.2 Anon. Professor Ginés Morata ForMemRS. royalsociety.org. London: Royal Society. 2017 [2016-03-09]. (原始内容存档于2016-11-11). 
  4. ^ Morata, Ginés; Struhl, Gary. Developmental biology: Tethered wings. Nature. 2014, 505 (7482): 162–163. ISSN 1476-4687. PMID 24390347. doi:10.1038/nature12848.  付费文献
  5. ^ 5.0 5.1 5.2 Ginés Morata Pérez. rioja.es. (原始内容存档于2018-12-21) (西班牙语). 
  6. ^ Ginés Morata. Herencia celular de la determinación en Drosophila. ProQuest. [2018-12-20]. (原始内容存档于2019-12-11) (西班牙语). 
  7. ^ Morata Pérez, Ginés. Herencia celular de la determinación en Drosophila. proquest.com (PhD论文) (Universidad Complutense de Madrid). 1973 [2018-12-21]. OCLC 911990833. (原始内容存档于2019-12-11). 
  8. ^ Herrera, Salvador C.; Morata, Ginés. Transgressions of compartment boundaries and cell reprogramming during regeneration in Drosophila. eLife. 2014, 3: e01831. ISSN 2050-084X. PMC 3989595可免费查阅. PMID 24755288. doi:10.7554/eLife.01831.  开放获取
  9. ^ Ballesteros-Arias, L.; Saavedra, V.; Morata, G. Cell competition may function either as tumour-suppressing or as tumour-stimulating factor in Drosophila. Oncogene. 2014, 33 (35): 4377–4384. ISSN 1476-5594. PMID 24096487. doi:10.1038/onc.2013.407.  付费文献
  10. ^ Morata, Ginés; Ballesteros-Arias, Luna. Cell competition, apoptosis and tumour development. The International Journal of Developmental Biology. 2015, 59 (1-3): 79–86. ISSN 1696-3547. PMID 26374529. doi:10.1387/ijdb.150081gm. 
  11. ^ Calleja, Manuel; Morata, Ginés; Casanova, Jordi. Tumorigenic Properties of Drosophila Epithelial Cells Mutant for lethal giant larvae. Developmental Dynamics. 2016, 245 (8): 834–843. ISSN 1097-0177. PMID 27239786. doi:10.1002/dvdy.24420. 
  12. ^ Morata, Ginés; Herrera, Salvador C. Eiger triggers death from afar. ELife. 2013, 2: e01388. ISSN 2050-084X. PMC 3780540可免费查阅. PMID 24069529. doi:10.7554/eLife.01388.  开放获取
  13. ^ Herrera, Salvador C.; Martín, Raquel; Morata, Ginés. Tissue homeostasis in the wing disc of Drosophila melanogaster: immediate response to massive damage during development. PLOS Genetics. 2013, 9 (4): e1003446. ISSN 1553-7404. PMC 3636033可免费查阅. PMID 23633961. doi:10.1371/journal.pgen.1003446.  开放获取
  14. ^ Reconocimiento. El biólogo Ginés Morata recibe su Doctorado Honoris Causa por la Universidad de Alcalá. Ibercampus. 2007-10-04 [2018-12-03]. 原始内容存档于2010-09-29 (西班牙语). 
  15. ^ Blanco Leal, M. Ginés Morata, Doctor Honoris Causa en su tierra. Ideal.es. 2008-04-14 [2018-12-20]. (原始内容存档于2018-05-04) (西班牙语). 
  16. ^ Gines Morata. National Academy of Sciences. [2018-12-20]. (原始内容存档于2020-10-28). 
  17. ^ PETER LAWRENCE Y GINÉS MORATA. Princess of Asturias Foundation. 2007-06-20 [2018-12-20]. 原始内容存档于2012-07-02. 

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