3-碘苯酚或间碘苯酚,是一种芳香族有机化合物。3-碘苯酚参与各种偶联反应,其中碘取代基被置换。[3]被广泛引用的例子包括硫醇盐[4]和胺亲核试剂。[5]
3-碘苯酚可由3-碘苯甲酸的氧化脱羧制备:[6]
- IC
6H
4CO
2H + "O" → IC
6H
4OH + CO
2
参考资料
- ^ 3-Iodophenol. Fisher Scientific. [2023-04-28]. (原始内容存档于2023-05-01).
- ^ Kwong, Fuk Yee; Buchwald, Stephen L. A General, Efficient, and Inexpensive Catalyst System for the Coupling of Aryl Iodides and Thiols. Organic Letters. 2002, 4 (20): 3517–3520. PMID 12323058. doi:10.1021/ol0266673.
- ^ Shen, Qilong; Ogata, Tokutaro; Hartwig, John F. Highly Reactive, General and Long-Lived Catalysts for Palladium-Catalyzed Amination of Heteroaryl and Aryl Chlorides, Bromides, and Iodides: Scope and Structure–Activity Relationships. Journal of the American Chemical Society. 2008, 130 (20): 6586–6596. PMC 2822544 . PMID 18444639. doi:10.1021/ja077074w.
- ^ Xiong, Wenzhang; Shi, Qiu; Liu, Wenbo H. Simple and Practical Conversion of Benzoic Acids to Phenols at Room Temperature. Journal of the American Chemical Society. 2022, 144 (34): 15894–15902. PMID 35997485. S2CID 251742827. doi:10.1021/jacs.2c07529.
参考书目