Oxidized cellulose is a water-insoluble derivative of cellulose . It can be produced from cellulose by the action of an oxidizing agent, such as chlorine , hydrogen peroxide , peracetic acid , chlorine dioxide , nitrogen dioxide , persulfates , permanganate , dichromate-sulfuric acid , hypochlorous acid , hypohalites or periodates and a variety of metal catalysts .[ 1] Oxidized cellulose may contain carboxylic acid , aldehyde , and/or ketone groups, in addition to the original hydroxyl groups of the starting material, cellulose , depending on the nature of the oxidant and reaction conditions.[ 2]
It is an antihemorrhagic .[ 3] It works both by absorbing the blood (similar to a cotton ball)[ 4] and by triggering the contact activation system . It is poorly absorbed and may cause healing complications postoperatively.[ 5]
See also
References
^ Collinson SR, Thielemans W (August 2010). "The catalytic oxidation of biomass to new materials focusing on starch, cellulose and lignin" (PDF) . Coordination Chemistry Reviews . 254 (15–16): 1854–1870. doi :10.1016/j.ccr.2010.04.007 .
^ US 5780618 , Banker GS, Kumar V, "Oxidized cellulose", issued 14 July 1998, assigned to Biocontrol Inc.
^ Oto A, Remer EM, O'Malley CM, Tkach JA, Gill IS (June 1999). "MR characteristics of oxidized cellulose (Surgicel)" . AJR. American Journal of Roentgenology . 172 (6): 1481–1484. doi :10.2214/ajr.172.6.10350276 . PMID 10350276 .
^ "Oxidised Cellulose" . Advanced Medical Solutions Group plc . 30 November 2023.
^ Resnik RR (2018). "Intraoperative Complications". In Resnik RR, Misch CE (eds.). Misch's Avoiding Complications in Oral Implantology . pp. 267–293. doi :10.1016/B978-0-323-37580-1.00007-X . ISBN 978-0-323-37580-1 .