CCL26

CCL26
[[Datei:|250x200px|CCL26]]
CCL26
Andere Namen
  • Chemokine (C-C Motif) Ligand 26
  • Macrophage Inflammatory Protein 4-Alpha
  • Thymic Stroma Chemokine-1
  • CC Chemokine IMAC
  • Eotaxin-3
  • SCYA26
  • Small Inducible Cytokine Subfamily A (Cys-Cys), Member 26
  • Chemokine N1
  • MIP-4-Alpha
  • TSC-1
  • IMAC

Vorhandene Strukturdaten: 1G2S, 1G2T

Eigenschaften des menschlichen Proteins
Masse/Länge Primärstruktur 94 Aminosäuren, 10648 Da
Bezeichner
Externe IDs
Vorkommen
Homologie-Familie Hovergen

CCL26 (englisch CC-chemokine ligand 26) ist ein Zytokin aus der Familie der CC-Chemokine.

Eigenschaften

CCL26 ist an Entzündungsprozessen beteiligt. Es wird im Herz, in der Lunge, in den Eierstöcken und in Interleukin-4-stimulierten Endothelzellen gebildet.[1][2] CCL26 bindet an den Rezeptor CCR3 auf Eosinophilen und Basophilen.[3]

Einzelnachweise

  1. ↑ Shinkai et al. A novel human CC chemokine, eotaxin-3, which is expressed in IL-4-stimulated vascular endothelial cells, exhibits potent activity toward eosinophils. J. Immunol. 163:1602-1610, 1999.
  2. ↑ Guo et al. Molecular cloning and characterization of a novel human CC chemokine, SCYA26. Genomics 58:313-317, 1999.
  3. ↑ Kitaura et al. Molecular cloning of a novel human CC chemokine (Eotaxin-3) that is a functional ligand of CC chemokine receptor 3. J. Biol. Chem. 274:27975-27980, 1999.

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