E2F
E2F Transcription Factor 1; Retinoblastoma-Associated Protein 1; Retinoblastoma-Binding Protein 3; PRB-Binding Protein E2F-1; RBAP-1; RBBP-3; RBBP3; E2F-1; PBR3…
| E2F1 | ||
|---|---|---|
| Andere Namen |
E2F Transcription Factor 1; Retinoblastoma-Associated Protein 1; Retinoblastoma-Binding Protein 3; PRB-Binding Protein E2F-1; RBAP-1; RBBP-3; RBBP3; E2F-1; PBR3; Transcription Factor E2F1; RBAP1; RBP3 | |
| Eigenschaften des menschlichen Proteins | ||
| Masse/Länge Primärstruktur | 437 Aminosäuren, 46920 Da | |
| Bezeichner | ||
| Externe IDs | ||
| Vorkommen | ||
| Homologie-Familie | Hovergen | |
| Orthologe | ||
| Mensch | Hausmaus | |
| Entrez | 1869 | 13555 |
| UniProt | Q01094 | Q61501 |
| Refseq (mRNA) | NM_005225 | |
| Refseq (Protein) | NP_005216 | |
| Genlocus | Chr 20: 33.68 – 33.69 Mb | |
| PubMed-Suche | 1869 | 13555
|
E2F ist eine Familie von Transkriptionsfaktoren in Eukaryoten.[1] Drei Vertreter der Familie aktivieren die Transkription von Genen (E2F1, 2 und E2F3a), sechs hemmen die Transkription (E2F3b, E2F4-8).
Literatur
- Jeremy M. Berg, John L. Tymoczko, Lubert Stryer: Biochemie. 6. Auflage, Spektrum Akademischer Verlag, Heidelberg 2007, ISBN 978-3-8274-1800-5.
- Donald Voet, Judith G. Voet: Biochemistry. 3. Auflage. John Wiley & Sons, New York 2004, ISBN 0-471-19350-X.
- Bruce Alberts, Alexander Johnson, Peter Walter, Julian Lewis, Martin Raff, Keith Roberts: Molecular Biology of the Cell. 5. Auflage. Taylor & Francis, 2007, ISBN 978-0-8153-4106-2.
Einzelnachweise
- ↑ C. Schaal, S. Pillai, S. P. Chellappan: The Rb-E2F transcriptional regulatory pathway in tumor angiogenesis and metastasis. In: Adv Cancer Res. Band 121, 2014, S. 147–182. doi:10.1016/B978-0-12-800249-0.00004-4. PMID 24889531.
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