SMURF2

SMAD Specific E3 Ubiquitin Protein Ligase 2; SMAD-Specific E3 Ubiquitin-Protein Ligase 2; SMAD Ubiquitination Regulatory Factor 2; HSMURF2; E3 Ubiquitin-Protein…

SMURF2
SMURF2
Andere Namen

SMAD Specific E3 Ubiquitin Protein Ligase 2; SMAD-Specific E3 Ubiquitin-Protein Ligase 2; SMAD Ubiquitination Regulatory Factor 2; HSMURF2; E3 Ubiquitin-Protein Ligase SMURF2; E3 Ubiquitin Ligase SMURF2; EC 6.3.2.-; EC 6.3.2

Vorhandene Strukturdaten: 1ZVD, 2DJY, 2JQZ, 2KXQ, 2LTZ

Eigenschaften des menschlichen Proteins
Masse/Länge Primärstruktur 748 Aminosäuren, 86196 Da
Bezeichner
Externe IDs
Vorkommen
Homologie-Familie Hovergen
Orthologe
Mensch Hausmaus
Entrez 64750 66313
UniProt Q9HAU4 A2A5Z6
PubMed-Suche 64750 66313

Struktur des SMURF2-Proteins. Basierend auf PyMOL-Rendering

SMURF2 ist eine Ubiquitin-Protein-Ligase, die SMAD-Proteine mit dem Protein Ubiquitin versieht.[1]

Einzelnachweise

  1. ↑ D. David, S. A. Nair, M. R. Pillai: Smurf E3 ubiquitin ligases at the cross roads of oncogenesis and tumor suppression. In: Biochim Biophys Acta. Band 1835, Heft 1, 2013, S. 119–128. doi:10.1016/j.bbcan.2012.11.003. PMID 23164545.

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