This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:deoxyguanosine 5'-phosphotransferase. Other names in common use include deoxyguanosine kinase (phosphorylating), (dihydroxypropoxymethyl)guanine kinase, 2'-deoxyguanosine kinase, and NTP-deoxyguanosine 5'-phosphotransferase. This enzyme participates in purine metabolism.
Structural studies
As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes 2JAQ, 2JAS, 2JAT, and 2OCP.
Barker J, Lewis RA (1981). "Deoxyguanosine kinase of neonatal mouse skin tissue". Biochim. Biophys. Acta. 658 (1): 111–23. doi:10.1016/0005-2744(81)90254-0. PMID6260206.
Gower Jr WR, Carr MC, Ives DH (1979). "Deoxyguanosine kinase. Distinct molecular forms in mitochondria and cytosol". J. Biol. Chem. 254 (7): 2180–3. PMID218928.