Astikas was one of the sons of Kristinas Astikas. He was first mentioned in written sources in the 1411 Treaty of Melno.[1] He was Grand Duke's marshal in 1420–29 and 1440–52.[1] Radvila Astikas was Voivode of Trakai (1466–77) and Castellan of Vilnius (1475–77), as well as Grand Marshal of Lithuania (1433–34, 1463–74).[2] He was sent to several diplomatic missions: to Teutonic Knights in 1466, 1447, and 1448, to Golden Horde in 1452.[1] He also participated in negotiating the 1473 Treaty of Kurcums which defined the Lithuanian–Livonian border.[3] There were rumors that in 1440 Astikas was considered as a candidate to the Grand Duke's throne instead of Casimir Jagiellon, but they should be taken with a grain of salt.[4]
His wife's name or origin is unknown.[1][9] His son Mikalojus Radvila nicknamed "the Old" was the first to carry "Radvila" as a family name. His daughter Anna married Petka Jogailavičius (Petko Jagojłowicz).[1][9] Astikas and his wife Eudoxia were the great-great-great grandparents of Elizabeth Báthory.