FRK

Quinasa asociada a Fyn
Estructuras disponibles
PDB Buscar ortólogos: PDBe, RCSB
Identificadores
Símbolos FRK (HGNC: 3955) GTK; PTK5; RAK
Identificadores
externos
  • GeneCards: Gen FRK
  • UniProt: FRK
    • Locus Cr. 6 q22.1
    Ortólogos
    Especies
    Humano Ratón
    Entrez
    2444
    UniProt
    P42685 n/a
    RefSeq
    (ARNm)
    NP_002022 n/a
    [editar datos en Wikidata]

    La quinasa asociada a Fyn (FRK o anteriormente tirosina quinasa 5) es una enzima codificada en humanos por el gen HGNC FRK .[1]​[2]​

    La proteína codificada por este gen pertenece a la familia de las tirosina quinasas. Esta enzima es una proteína nuclear que podría actuar durante las fases G1 y S del ciclo celular, impidiendo la proliferación celular.[2]​

    Interacciones

    La proteína FRK ha demostrado ser capaz de interaccionar con:

    Referencias

    1. ↑ Lee J, Wang Z, Luoh SM, Wood WI, Scadden DT (Apr de 1994). «Cloning of FRK, a novel human intracellular SRC-like tyrosine kinase-encoding gene». Gene 138 (1-2): 247-51. PMID 7510261. 
    2. ↑ a b «Entrez Gene: FRK fyn-related kinase». 
    3. ↑ Craven, R J; Cance W G, Liu E T (Sep. de 1995). «The nuclear tyrosine kinase Rak associates with the retinoblastoma protein pRb». Cancer Res. (UNITED STATES) 55 (18): 3969-72. ISSN 0008-5472. PMID 7664264. 

    Enlaces externos

    • En HomoloGene: FRK

    https://raresource.nih.gov/diseases/filter/0000550/

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