Hispidín

Hispidina es una sustancia natural que también se puede sintetizar.[2]​

Hispidín
 
Hispidina
Nombre IUPAC
2-[(E)-2-(3,4-dihydroxyphenyl)ethenyl]-6-hydroxypyran-4-one
General
Otros nombres 6-(3,4-dihydroxystyrl)-4-hydroxy-2-pyrone
Fórmula estructural Imagen de la estructura
Fórmula molecular C
13H
10O
5
Identificadores
Número CAS 555-55-5[1]​
ChEBI 36332
ChEMBL CHEMBL1224512
ChemSpider 13975015
PubChem 5353671
UNII SSJ18CG55E
C1=CC(=C(C=C1C=CC2=CC(=O)C=C(O2)O)O)O
InChI=1S/C13H10O5/c14-9-6-10(18-13(17)7-9)3-1-8-2-4-11(15)12(16)5-8/h1-7,14-16H/b3-1+
Key: SGJNQVTUYXCBKH-HNQUOIGGSA-N
Propiedades físicas
Masa molar 246,21 g/mol
Valores en el SI y en condiciones estándar
(25 ℃ y 1 atm), salvo que se indique lo contrario.
[editar datos en Wikidata]

Hispidina es una sustancia natural que también se puede sintetizar.[2]​

Hispidina 4-O-β-d-glucopiranosido se puede encontrar en Pteris ensiformis[3]​ mientras que los derivados de hispidina, tales como phellibaumin, se puede encontrar en el hongo comestible Inonotus xeranticus[4]​ o Phellinus.[5]​[6]​


Referencias

  1. ↑ Número CAS
  2. ↑ Gonindard, C.; Bergonzi, C.; Denier, C.; Sergheraert, C.; Klaebe, A.; Chavant, L.; Hollande, E. (1997). «Synthetic hispidin, a PKC inhibitor, is more cytotoxic toward cancer cells than normal cells in vitro». Cell Biology and Toxicology 13 (3): 141-53. PMID 9088624. doi:10.1023/A:1007321227010. 
  3. ↑ Identification of phenolic antioxidants from Sword Brake fern (Pteris ensiformis Burm.). Yung-Husan Chen, Fang-Rong Chang, Yih-Jer Lin, Lisu Wang, Jinn-Fen Chen, Yang-Chang Wu and Ming-Jiuan Wu, Food Chemistry, Volume 105, Issue 1, 2007, pp. 48-56, doi 10.1016/j.foodchem.2007.03.055
  4. ↑ Hispidin Derivatives from the Mushroom Inonotus xeranticus and Their Antioxidant Activity. In-Kyoung Lee, Soon-Ja Seok, Wan-Kyu Kim and Bong-Sik Yun, J. Nat. Prod., 2006, 69 (2), pp. 299–301, doi 10.1021/np050453n
  5. ↑ Lee, In-Kyoung; Yun, Bong-Sik (2007). «Highly oxygenated and unsaturated metabolites providing a diversity of hispidin class antioxidants in the medicinal mushrooms Inonotus and Phellinus». Bioorganic & Medicinal Chemistry 15 (10): 3309-14. PMID 17387019. doi:10.1016/j.bmc.2007.03.039. 
  6. ↑ Lee, Yeon Sil; Kang, Young-Hee; Jung, Ju-Young; Lee, Sanghyun; Ohuchi, Kazuo; Shin, Kuk Hyun; Kang, Il-Jun; Park, Jung Han Yoon et al. (octubre de 2008). «Protein glycation inhibitors from the fruiting body of Phellinus linteus» (Uso incorrecto de la plantilla enlace roto (enlace roto disponible en Internet Archive; véase el historial, la primera versión y la última).). Biological & Pharmaceutical Bulletin 31 (10): 1968-72. PMID 18827365. doi:10.1248/bpb.31.1968. 

Enlaces externos

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