TUBB

La cadena beta de tubulina (TUBB del inglés Tubulin beta) es una proteína codificada en humanos por el gen TUBB.[1]​[2]​[3]​

TUBB
Cadena beta de tubulina

Estructura tridimensional de la proteína TUBB.
PDB
Lista de códigos PDB
1ffx
Identificadores
Símbolos TUBB (HGNC: 20778) TUBB5; TUBB1; M40; MGC117247; MGC16435; OK/SW-cl.56
Identificadores
externos
  • GeneCards: Gen TUBB
  • UniProt: TUBB
  • Locus Cr. 6 p21
    Ortólogos
    Especies
    Humano Ratón
    Entrez
    203068
    RefSeq
    (ARNm)
    NP_821133 n/a

    La cadena beta de tubulina (TUBB del inglés Tubulin beta) es una proteína codificada en humanos por el gen TUBB.[1][2][3]

    Tiene una estructura primaria de 444 aminoácidos y un peso molecular de 49.671 Da.[4]

    Interacciones

    La proteína TUBB ha demostrado ser capaz de interaccionar con:

    Véase también

    Referencias

    1. Crabtree, D. V.; Ojima, I.; Geng, X.; Adler, A. J. (2001-08). «Tubulins in the primate retina: evidence that xanthophylls may be endogenous ligands for the paclitaxel-binding site». Bioorganic & Medicinal Chemistry 9 (8): 1967-1976. ISSN 0968-0896. PMID 11504633. doi:10.1016/s0968-0896(01)00103-1. Consultado el 12 de octubre de 2020. 
    2. Volz, A.; Weiss, E.; Trowsdale, J.; Ziegler, A. (1994-01). «Presence of an expressed beta-tubulin gene (TUBB) in the HLA class I region may provide the genetic basis for HLA-linked microtubule dysfunction». Human Genetics 93 (1): 42-46. ISSN 0340-6717. PMID 8270253. doi:10.1007/BF00218911. Consultado el 12 de octubre de 2020. 
    3. «Entrez Gene: TUBB tubulin, beta». 
    4. «Tubulin beta chain». Uniprot. 
    5. Goo, Young-Hwa; Sohn Young Chang, Kim Dae-Hwan, Kim Seung-Whan, Kang Min-Jung, Jung Dong-Ju, Kwak Eunyee, Barlev Nickolai A, Berger Shelley L, Chow Vincent T, Roeder Robert G, Azorsa David O, Meltzer Paul S, Suh Pan-Gil, Song Eun Joo, Lee Kong-Joo, Lee Young Chul, Lee Jae Woon (Jan. de 2003). «Activating signal cointegrator 2 belongs to a novel steady-state complex that contains a subset of trithorax group proteins». Mol. Cell. Biol. (United States) 23 (1): 140-9. ISSN 0270-7306. PMID 12482968. 
    6. Haberman, Yael; Grimberg Elena, Fukuda Mitsunori, Sagi-Eisenberg Ronit (Nov. de 2003). «Synaptotagmin IX, a possible linker between the perinuclear endocytic recycling compartment and the microtubules». J. Cell. Sci. (England) 116 (Pt 21): 4307-18. ISSN 0021-9533. PMID 12966166. doi:10.1242/jcs.00719. 

    Enlaces externos

    • En Genome:TUBB
    • En MalaCards.Enfermedades que coinciden con:TUBB

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