USP8

La ubiquitina carboxil-terminal hidrolasa 8 es una enzima que en humanos está codificada por el gen USP8.[1]​[2]​[3]​

Interacciones

Se ha demostrado que USP8 interactúa con RNF41[4]​ y STAM2.[5]​[6]​

Referencias

  1. ↑ «Human and mouse proteases: a comparative genomic approach». Nat Rev Genet 4 (7): 544-58. July 2003. PMID 12838346. doi:10.1038/nrg1111. 
  2. ↑ «An oncogenic fusion product of the phosphatidylinositol 3-kinase p85beta subunit and HUMORF8, a putative deubiquitinating enzyme». Oncogene 16 (13): 1767-72. May 1998. PMID 9582025. doi:10.1038/sj.onc.1201695. 
  3. ↑ «Entrez Gene: USP8 ubiquitin specific peptidase 8». 
  4. ↑ Wu, Xiuli; Yen Lily; Irwin Lisa; Sweeney Colleen; Carraway Kermit L (September 2004). «Stabilization of the E3 ubiquitin ligase Nrdp1 by the deubiquitinating enzyme USP8». Mol. Cell. Biol. 24 (17): 7748-57. ISSN 0270-7306. PMC 506982. PMID 15314180. doi:10.1128/MCB.24.17.7748-7757.2004. 
  5. ↑ Kaneko, Tomonori; Kumasaka Takashi; Ganbe Tadashi; Sato Takao; Miyazawa Keiji; Kitamura Naomi; Tanaka Nobuo (November 2003). «Structural insight into modest binding of a non-PXXP ligand to the signal transducing adaptor molecule-2 Src homology 3 domain». J. Biol. Chem. 278 (48): 48162-8. ISSN 0021-9258. PMID 13129930. doi:10.1074/jbc.M306677200. 
  6. ↑ Kato, M; Miyazawa K; Kitamura N (December 2000). «A deubiquitinating enzyme UBPY interacts with the Src homology 3 domain of Hrs-binding protein via a novel binding motif PX(V/I)(D/N)RXXKP». J. Biol. Chem. 275 (48): 37481-7. ISSN 0021-9258. PMID 10982817. doi:10.1074/jbc.M007251200. 

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