Abieta-7,13-dien-18-al dehidrogenaza

Abieta-7,13-dien-18-al dehidrogenaza
Identifikatori
EC broj	1.2.1.74
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB	RCSB PDB PDBe PDBj PDBsum
Pretraga
PMC	articles
PubMed	articles
NCBI Protein	search

Abieta-7,13-dien-18-al dehidrogenaza (EC 1.2.1.74, abietadienalna dehidrogenaza (ambiguous)) je enzim sa sistematskim imenom abieta-7,13-dien-18-al:NAD⁺ oksidoreduktaza.^[1]^[2] Ovaj enzim katalizuje sledeću hemijsku reakciju

abieta-7,13-dien-18-al +H₂O + NAD⁺

\rightleftharpoons

abieta-7,13-dien-18-oat + NADH + H⁺

Abietska kiselina je glavna komponenta smole četinara. Ovaj enzim katalizuje zadnji korak u biosintezi abietske kiselina kod Abies grandis.

Reference

↑ Funk, C. and Croteau, R. (1994). „Diterpenoid resin acid biosynthesis in conifers: characterization of two cytochrome P450-dependent monooxygenases and an aldehyde dehydrogenase involved in abietic acid biosynthesis”. Arch. Biochem. Biophys. 308: 258-266. PMID 8311462.
↑ Funk, C., Lewinsohn, E., Vogel, B.S., Steele, C.L. and Croteau, R. (1994). „Regulation of oleoresinosis in grand fir (Abies grandis) (coordinate induction of monoterpene and diterpene cyclases and two cytochrome P450-dependent diterpenoid hydroxylases by stem wounding)”. Plant Physiol. 106: 999-1005. PMID 12232380.

Literatura

Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.

Vanjske veze

MeSH Abieta-7,13-dien-18-al+dehydrogenase

[1] Funk, C. and Croteau, R. (1994). „Diterpenoid resin acid biosynthesis in conifers: characterization of two cytochrome P450-dependent monooxygenases and an aldehyde dehydrogenase involved in abietic acid biosynthesis”. Arch. Biochem. Biophys. 308: 258-266. PMID 8311462.

[2] Funk, C., Lewinsohn, E., Vogel, B.S., Steele, C.L. and Croteau, R. (1994). „Regulation of oleoresinosis in grand fir (Abies grandis) (coordinate induction of monoterpene and diterpene cyclases and two cytochrome P450-dependent diterpenoid hydroxylases by stem wounding)”. Plant Physiol. 106: 999-1005. PMID 12232380.

[1]

[2]