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Piknoporopepsin

Piknoporopepsin
Identifikatori
EC broj 3.4.23.30
CAS broj 77967-78-3
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB RCSB PDB PDBe PDBj PDBsum

Piknoporopepsin (EC 3.4.23.30, proteinaza Ia, Pycnoporus coccineus aspartinska proteinaza, Trametes kiselinskaa proteinaza) je enzim.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju

Slična specifičnost sa pepsinom A, mada uža. Odavajaju se samo tri veze u B lancu insulina: Ala14-Leu, Tyr16-Leu, i Phe24-Phe

Ovaj enzim je prisutan in bazidiomiceti Pycnoporus sanguineus .

Reference

  1. ↑ Tomoda, K. and Shimazono, H. (1964). „Acid protease produced by Trametes sanguinea a wood-destroying fungus. Part I. Purification and crystallization of the enzyme”. Agric. Biol. Chem. 28: 770-773. 
  2. ↑ Tsuru, D., Hattori, A., Tsuji, H., Yamamoto, T. and Fukumoto, J. (1969). „Studies on mold proteases. Part II. Substrate specificity of acid protease of Rhizopus chinensis”. Agric. Biol. Chem. 33: 1419-1426. 
  3. ↑ Ichishima, E., Kumagai, H. and Tomoda, K. (1980). „Substrate specificity of carboxyl proteinase from Pycnoporus coccineus, a wood-deteriorating fungus”. Curr. Microbiol. 3: 333-337. 

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