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Praktolol

Praktolol
IUPAC ime
(RS)-N- {4-[2-hidroksi-3-(izopropilamino)propoksi]fenil}acetamid
Identifikatori
CAS broj6673-35-4 ДаY
ATC kodC07AB01 (WHO)
PubChemCID 4883
IUPHAR/BPS555
DrugBankDB01297 ДаY
ChemSpider4715 ДаY
UNIISUG9176GRW ДаY
KEGGD05587 ДаY
ChEBICHEBI:258351 ДаY
ChEMBLCHEMBL6995 ДаY
Hemijski podaci
FormulaC14H22N2O3
Molarna masa266,336 g/mol
  • O=C(Nc1ccc(OCC(O)CNC(C)C)cc1)C
  • InChI=1S/C14H22N2O3/c1-10(2)15-8-13(18)9-19-14-6-4-12(5-7-14)16-11(3)17/h4-7,10,13,15,18H,8-9H2,1-3H3,(H,16,17) ДаY
  • Key:DURULFYMVIFBIR-UHFFFAOYSA-N ДаY

Practolol (Eraldin, Dalzic, Praktol, Cardiol, Pralon, Cordialina, Eraldina, Teranol) selektivni je beta blokator koji je korišten u lečenju srčanih aritmija. Praktolol nije više u upotrebi jer je veoma toksičan uprkos toga što je hemijski veoma sličan sa propanololom.[1]

Nuspojave

Nuspojave ovog leka su tipične za beta blokatore: bronhokonstrikcija, zatajenje srca, zamor, depresija i hipoglikemija.[2]

Zabrana

Praktolol je zabranjen u Indiji.[3]

Reference

  1. ^ British Medical Journal, March 15, 1975
  2. ^ Rod Flower; Humphrey P. Rang; Maureen M. Dale; Ritter, James M. (2007). Rang & Dale's pharmacology. Edinburgh: Churchill Livingstone. ISBN 0-443-06911-5. 
  3. ^ „Drugs banned in India”. Central Drugs Standard Control Organization, Dte.GHS, Ministry of Health and Family Welfare, Government of India. Архивирано из оригинала 21. 02. 2015. г. Приступљено 17. 9. 2013. 

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