AMY2A

AMY2A
Struktur yang tersedia
PDBPencarian ortolog: PDBe RCSB
Pengidentifikasi
AliasAMY2A, AMY2, AMY2B, PA, amylase, alpha 2A (pancreatic), amylase alpha 2A (pancreatic), amylase alpha 2A
ID EksternalOMIM: 104650; MGI: 88019; HomoloGene: 20179; GeneCards: AMY2A; OMA:AMY2A - orthologs
Nomor EC3.2.1.1
Ortologi
SpesiesManusiaTikus
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_000699

NM_001110505
NM_007446

RefSeq (protein)

NP_000690

NP_001103975
NP_031472

Location (UCSC)Chr 1: 103.62 – 103.63 Mbn/a
PubMed search[2][3]
Wikidata
Lihat/Sunting ManusiaLihat/Sunting Tikus

Alfa-amilase pankreas adalah enzim yang pada manusia disandikan oleh gen AMY2A.[4][5]

Amilase merupakan protein sekretori yang menghidrolisis ikatan 1,4-alfa-glukosida dalam oligosakarida dan polisakarida, sehingga mengatalisis langkah pertama dalam pencernaan pati dan glikogen makanan. Genom manusia memiliki klaster dari beberapa gen amilase yang diekspresikan pada tingkat tinggi baik di kelenjar ludah maupun pankreas. Gen ini menyandikan isoenzim amilase yang diproduksi oleh pankreas.[5]

Lihat pula

Referensi

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000243480Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ Groot PC, Bleeker MJ, Pronk JC, Arwert F, Mager WH, Planta RJ, Eriksson AW, Frants RR (Jul 1988). "Human pancreatic amylase is encoded by two different genes". Nucleic Acids Res. 16 (10): 4724. doi:10.1093/nar/16.10.4724. PMC 336663. PMID 3260028.
  5. ^ a b "Entrez Gene: AMY2A amylase, alpha 2A; pancreatic".

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