4C-T-2

4C-T-2
Clinical data
ATC code	none;
Legal status
Legal status	In general: uncontrolled;
Identifiers
	IUPAC name 1-[(2,5-dimethoxy-4-ethylthio)phenyl]butan-2-amine;
CAS Number	850007-13-5 ; 849919-79-5 (hydrochloride);
PubChem CID	11197523;
ChemSpider	9372592 ;
UNII	AY9HDQ4A2H;
ChEMBL	ChEMBL372719 ;
CompTox Dashboard (EPA)	DTXSID001029306 ;
Chemical and physical data
Formula	C14H23NO2S
Molar mass	269.40 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES COC1=C(CC(CC)N)C=C(OC)C(SCC)=C1;
	InChI InChI=1S/C14H23NO2S/c1-5-11(15)7-10-8-13(17-4)14(18-6-2)9-12(10)16-3/h8-9,11H,5-7,15H2,1-4H3 ; Key:KLAWPCIXPDTGCZ-UHFFFAOYSA-N ;
	(verify)

2,5-Dimethoxy-4-ethylthio-α-ethylphenethylamine (4C-T-2) is a synthetic drug of the phenethylamine chemical class. It is the α-ethylated analogue of 2C-T-2.

Pharmacology

4C-T-2 has affinity (K_i) for the 5-HT_1A (5,339 nM), 5-HT_1E (9,879 nM), 5-HT_2A (274.1 nM), 5-HT_2B (58.1 nM), 5-HT_2C (468.6 nM), 5-HT_5A (1,587 nM), 5-HT₇ (3,829), D₃ (1,273 nM), β₂-adrenergic (124.9 nM), I₁ (946.5 nM), and σ₁ (514 nM) receptors.^[1] The activity of 4C-T-2 at these sites has not been assayed, with the exception of the 5-HT_2A and 5-HT_2C receptors where it acts as a partial agonist.^[1]

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