Euparin

weißer geruchloser Feststoff[1]

Euparin
Strukturformel
Strukturformel von Euparin
Allgemeines
Name Euparin
Andere Namen
  • 5-Acetyl-6-hydroxy-2-isopropylbenzofuran
  • 1-(6-hydroxy-2-prop-1-en-2-yl-1-benzofuran-5-yl)ethanon
Summenformel C13H12O3
Kurzbeschreibung

weißer geruchloser Feststoff[1]

Externe Identifikatoren/Datenbanken
CAS-Nummer 532-48-9
PubChem 119039
ChemSpider 106366
Wikidata Q27135902
Eigenschaften
Molare Masse 216,236 g·mol−1
Aggregatzustand

fest[1]

Schmelzpunkt

121–122 °C[1]

Sicherheitshinweise
GHS-Gefahrstoffkennzeichnung[1]
Gefahrensymbol

Achtung

H- und P-Sätze H: 315​‐​319​‐​335
P: 280​‐​261​‐​305+351+338​‐​321​‐​405​‐​501[1]
Wenn nicht anders vermerkt, gelten die angegebenen Daten bei Standardbedingungen (0 °C, 1000 hPa).

Euparin ist eine chemische Verbindung aus der Gruppe der Benzofurane.[2] Euparin kommt in verschiedenen Pflanzenarten der Tribus Eupatorieae vor, unter anderem in der Gattung Eupatorium (Eupatorium buniifolium,[3] Eupatorium chinensis,[4] Eupatorium purpureum[5]), aber auch in Helianthus tuberosus,[6] Petasites albus (73 % des Öls),[7] Ligularia caloxantha,[8] Ligularia stenocephala[9] und Helianthella quinquenervis.[10]

Euparin besitzt im Plaque-Assay antivirale Wirkung gegen das Poliovirus.[3]

Einzelnachweise

  1. ↑ a b c d e LGC: Sicherheitsdatenblatt Euparin (Memento vom 10. März 2018 im Internet Archive)
  2. ↑ Ahmed Mustafa: Benzofurans. John Wiley & Sons, 2009, ISBN 978-0-470-18850-7, S. 299.
  3. ↑ a b M. F. Visintini Jaime, R. H. Campos, V. S. Martino, L. V. Cavallaro, L. V. Muschietti: Antipoliovirus Activity of the Organic Extract of Eupatorium buniifolium: Isolation of Euparin as an Active Compound. In: Evidence-based complementary and alternative medicine : eCAM. Band 2013, 2013, S. 402364, doi:10.1155/2013/402364, PMID 23956770, PMC 3730360 (freier Volltext).
  4. ↑ X. L. Xie, X. J. Xu, R. M. Li, J. Z. Wan, C. Y. Xie, D. P. Yang, X. Chen: Isolation and simultaneous determination of two benzofurans in Radix Eupatorii Chinensis. In: Natural Product Research. Band 24, Nummer 19, November 2010, S. 1854–1860, doi:10.1080/14786419.2010.482935, PMID 21104532.
  5. ↑ S. Habtemariam: Antiinflammatory activity of the antirheumatic herbal drug, gravel root (Eupatorium purpureum): further biological activities and constituents. In: Phytotherapy research : PTR. Band 15, Nummer 8, Dezember 2001, S. 687–690, PMID 11746861.
  6. ↑ N. S. Radulović, M. R. Đorđević: Chemical composition of the tuber essential oil from Helianthus tuberosus L. (Asteraceae). In: Chemistry & biodiversity. Band 11, Nummer 3, März 2014, S. 427–437, doi:10.1002/cbdv.201300323, PMID 24634072.
  7. ↑ M. Mohammadi, M. Yousefi, Z. Habibi, D. Dastan: Chemical composition and antioxidant activity of the essential oil of aerial parts of Petasites albus from Iran: a good natural source of euparin. In: Natural Product Research. Band 26, Nummer 4, 2012, S. 291–297, doi:10.1080/14786410903374819, PMID 21416453.
  8. ↑ S. Y. Shi, M. H. Hu, D. Y. Wu, C. X. Zhou, J. X. Mo, J. H. Xu, L. R. Chen, H. Dou, H. Peng, X. J. Hao, J. Stöckigt, Y. Zhao: A new dibenzofuran and other constituents from Ligularia caloxantha, a Chinese medicinal plant. In: Natural Product Research. Band 22, Nummer 7, Mai 2008, S. 628–632, doi:10.1080/14786410701614218, PMID 18569702.
  9. ↑ K. Toyoda, Y. Yaoita, M. Kikuchi: Three new dimeric benzofuran derivatives from the roots of Ligularia stenocephala MATSUM. et KOIDZ. In: Chemical & pharmaceutical bulletin. Band 53, Nummer 12, Dezember 2005, S. 1555–1558, PMID 16327188.
  10. ↑ P. Castañeda, L. Gómez, R. Mata, B. Lotina-Hennsen, A. L. Anaya, R. Bye: Phytogrowth-inhibitory and antifungal constituents of Helianthella quinquenervis. In: Journal of natural products. Band 59, Nummer 3, März 1996, S. 323–326, doi:10.1021/np960199m, PMID 8882437.

Content Disclaimer

Informasi ini disarikan dari Wikipedia dan disajikan kembali untuk tujuan edukasi. Konten tersedia di bawah lisensi CC BY-SA 3.0. Kami tidak bertanggung jawab atas ketidakakuratan data yang bersumber dari kontribusi publik tersebut.

  1. The information displayed on this website is sourced in part or in whole from Wikipedia and has been adapted for the purpose of restating it. We strive to provide accurate and relevant information, however:
  2. There is no guarantee of absolute accuracy. Wikipedia is an open, collaborative project that can be edited by anyone, so information is subject to change.
  3. It is not intended to constitute professional advice. The content displayed is for informational and educational purposes only. For important decisions (e.g., medical, legal, or financial), please consult a professional.
  4. Content copyright. Wikipedia is licensed under the Creative Commons Attribution-ShareAlike License (CC BY-SA). This means that content may be reused with appropriate attribution and shared under a similar license.
  5. Responsible use. Any risk arising from the use of information from this website is entirely the responsibility of the user.