Kaliotoxin 2

Kaliotoxin-2, KTX-2

Potassium channel toxin alpha-KTx 3.5
Andere Namen

Kaliotoxin-2, KTX-2

Masse/Länge Primärstruktur 37 Aminosäuren
Präkursor 59 Aminosäuren, 6.393 Da
Bezeichner
Externe IDs

Kaliotoxin 2 (synonym Kaliumkanaltoxin alpha-KTx 3.5) ist ein Toxin aus dem Skorpion Androctonus australis.

Eigenschaften

Kaliotoxin 2 ist ein Protein und Skorpiontoxin aus A. australis, wie auch Kaliotoxin 1.[1] Es bindet und hemmt Dendrotoxin-sensitive spannungsgesteuerte Kaliumkanäle. Kaliotoxin 1 und 2 sind strukturell am nächsten mit Agitoxin 1, Agitoxin 2 und Agitoxin 3 verwandt.[2]

Einzelnachweise

  1. ↑ C. Legros, E. Feyfant, F. Sampieri, H. Rochat, P. E. Bougis, M. F. Martin-Eauclaire: Influence of a NH2-terminal extension on the activity of KTX2, a K+ channel blocker purified from Androctonus australis scorpion venom. In: FEBS letters. Band 417, Nummer 1, November 1997, S. 123–129, PMID 9395089.
  2. ↑ Hervé Rochat: Animal Toxins. Springer Science & Business Media, 2000, ISBN 978-3-764-35983-6, S. 184.

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