SARS-CoV-1

Koronavirus sindrom pernafasan akut teruk
	Imej mikroskop elektron virion SARS
Pengelasan virus
Templat taksonomi hilang (baiki):	Koronavirus berkaitan sindrom pernafasan akut teruk
Strain:	Koronavirus sindrom pernafasan akut teruk
Sinonim
	Koronavirus SARS; Koronavirus berkaitan SARS; Koronavirus sindrom pernafasan akut teruk;

Koronavirus sindrom pernafasan akut teruk (SARS-CoV atau SARS-CoV-1)^[2] merupakan baka virus yang menyebabkan sindrom pernafasan akut teruk (SARS).^[3] Ia merupakan satu menyelubungi, positif-rasa, tunggal terkandas virus RNA yang menjangkiti sel-sel epitelium dalam paru-paru.^[4] Virus memasuki sel inang dengan mengikat reseptor ACE2.^[5] Ia menjangkiti manusia, kelawar, dan musang sawit.^[6]^[7]

Pada 16 April 2003, berikutan wabak SARS di Asia dan kes sekunder di tempat lain di dunia, Pertubuhan Kesihatan Sedunia (WHO) mengeluarkan kenyataan akhbar yang menyatakan bahawa koronavirus yang dikenal pasti oleh sebilangan makmal ialah penyebab rasmi SARS. Pusat Kawalan dan Pencegahan Penyakit (CDC) di Amerika Syarikat dan Makmal Mikrobiologi Kebangsaan (NML) di Kanada mengenal pasti genom SARS-CoV pada April 2003.^[8]^[9] Para saintis di Universiti Erasmus di Rotterdam, Belanda menunjukkan bahawa koronavirus SARS memenuhi postulat Koch sehingga mengesahkannya sebagai agen penyebab. Dalam eksperimen tersebut, kera yang dijangkiti virus mengalami gejala yang sama dengan mangsa SARS manusia.^[10]

Pandemik koronavirus 2019-2020 penyakit koronavirus 2019 (COVID-19) menunjukkan banyak persamaan dengan wabak SARS, dengan agen virus yang dikenal pasti sebagai koronavirus sindrom pernafasan akut teruk 2 (SARS-CoV-2), namun satu lagi jenis Koronavirus berkaitan sindrom pernafasan akut teruk ( SARSr-CoV ). SARS-CoV-1 ialah salah satu daripada tujuh koronavirus yang diketahui menjangkiti manusia, termasuk Human coronavirus 229E (HCoV-229E), Human coronavirus NL63 ( HCoV-NL63 ), koronavirus manusia OC43 (HCoV-OC43), Human coronavirus HKU1 (HCoV-HK), Koronavirus berkaitan dengan sindrom pernafasan Timur Tengah (MERS-CoV), dan SARS-CoV-2.

Catatan

^ "ICTV Taxonomy history: Severe acute respiratory syndrome-related coronavirus" (html). International Committee on Taxonomy of Viruses (ICTV) (dalam bahasa Inggeris). Dicapai pada 27 January 2019.
^ Neeltje van Doremalen; Trenton Bushmaker; Dylan H. Morris; Myndi G. Holbrook; Amandine Gamble; Brandi N. Williamson; Azaibi Tamin; Jennifer L. Harcourt; Natalie J. Thornburg (17 March 2020). "Aerosol and Surface Stability of SARS-CoV-2 as Compared with SARS-CoV-1". The New England Journal of Medicine. doi:10.1056/NEJMc2004973. Dicapai pada 3 April 2020.
^ Thiel, V., penyunting (2007). Coronaviruses: Molecular and Cellular Biology (ed. 1st). Caister Academic Press. ISBN 978-1-904455-16-5.
^ Fehr, Anthony R.; Perlman, Stanley (2015). "Coronaviruses: An Overview of Their Replication and Pathogenesis". Coronaviruses. Methods in Molecular Biology. 1282. Clifton, New Jersey, USA. m/s. 1–23. doi:10.1007/978-1-4939-2438-7_1. ISBN 978-1-4939-2437-0. ISSN 1064-3745. PMC 4369385. PMID 25720466. SARS-CoV primarily infects epithelial cells within the lung. The virus is capable of entering macrophages and dendritic cells but only leads to an abortive infection [87,88].
^ Xing-Yi Ge; Jia-Lu Li; Xing-Lou Yang (2013). "Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor". Nature. 503 (7477): 535–538. Bibcode:2013Natur.503..535G. doi:10.1038/nature12711. PMC 5389864. PMID 24172901. Unknown parameter |displayauthors= ignored (bantuan)
^ "Global Epidemiology of Bat Coronaviruses". Viruses. 11 (2): 174. 20 February 2019. doi:10.3390/v11020174. ISSN 1999-4915. PMC 6409556. PMID 30791586. Most notably, horseshoe bats were found to be the reservoir of SARS-like CoVs, while palm civet cats are considered to be the intermediate host for SARS-CoVs [43,44,45].
^ "Receptor recognition and cross-species infections of SARS coronavirus". Antiviral Research. 100 (1): 246–254. October 2013. doi:10.1016/j.antiviral.2013.08.014. ISSN 0166-3542. PMC 3840050. PMID 23994189. See Figure 6.
^ "Remembering SARS: A Deadly Puzzle and the Efforts to Solve It". Centers for Disease Control and Prevention. 11 April 2013. Diarkibkan daripada yang asal pada 1 August 2013. Dicapai pada 3 August 2013.
^ "Coronavirus never before seen in humans is the cause of SARS". United Nations World Health Organization. 16 April 2006. Diarkibkan daripada yang asal pada 12 August 2004. Dicapai pada 5 July 2006.
^ "Aetiology: Koch's postulates fulfilled for SARS virus". Nature. 423 (6937): 240. 2003. Bibcode:2003Natur.423..240F. doi:10.1038/423240a. PMC 7095368. PMID 12748632. Unknown parameter |displayauthors= ignored (bantuan)

Rujukan

Peiris, J. S.; Lai, S. T.; Poon, L. L.; dll. (April 2003). "Coronavirus as a possible cause of severe acute respiratory syndrome". The Lancet. 361 (9366): 1319–1325. doi:10.1016/s0140-6736(03)13077-2. PMID 12711465.
Rota, P. A.; Oberste, M. S.; Monroe, S. S.; dll. (30 May 2003). "Characterization of a Novel Coronavirus Associated with Severe Acute Respiratory Syndrome" (PDF). Science. 300 (5624): 1394–1399. Bibcode:2003Sci...300.1394R. doi:10.1126/science.1085952. PMID 12730500.
Marra, Marco A.; dll. (30 May 2003). "The Genome Sequence of the SARS-Associated coronavirus". Science. 300 (5624): 1399–1404. Bibcode:2003Sci...300.1399M. doi:10.1126/science.1085953. PMID 12730501.
Snijder, E. J.; dll. (29 August 2003). "Unique and conserved features of genome and proteome of SARS-coronavirus, an early split-off from the coronavirus group 2 lineage". Journal of Molecular Biology. 331 (5): 991–1004. CiteSeerX 10.1.1.319.7007. doi:10.1016/S0022-2836(03)00865-9. PMID 12927536.
Yount, B.; dll. (15 August 2006). "Rewiring the severe acute respiratory syndrome coronavirus (SARS-CoV) transcription circuit: engineering a recombination-resistant genome". Proceedings of the National Academy of Sciences of the United States of America. 103 (33): 12546–12551. Bibcode:2006PNAS..10312546Y. doi:10.1073/pnas.0605438103. PMC 1531645. PMID 16891412.
Thiel, V., penyunting (2007). Coronaviruses: Molecular and Cellular Biology (ed. 1st). Caister Academic Press. ISBN 978-1-904455-16-5.
Enjuanes, L.; dll. (2008). "Coronavirus Replication and Interaction with Host". Animal Viruses: Molecular Biology. Caister Academic Press. ISBN 978-1-904455-22-6.

Pautan luar

WHO press release identifying and naming the SARS virus
The SARS virus genetic map Diarkibkan 2006-08-18 di Wayback Machine
Science special on the SARS virus (free content: no registration required)
McGill University SARS Resources di Wayback Machine (diarkibkan 1 Mac 2005)
U.S. Centers for Disease Control and Prevention (CDC) SARS home
World Health Organization on alert

[TaxHist-1] "ICTV Taxonomy history: Severe acute respiratory syndrome-related coronavirus" (html). International Committee on Taxonomy of Viruses (ICTV) (dalam bahasa Inggeris). Dicapai pada 27 January 2019.

[van_Doremalen_et_al.,_NEJM_2020-2] Neeltje van Doremalen; Trenton Bushmaker; Dylan H. Morris; Myndi G. Holbrook; Amandine Gamble; Brandi N. Williamson; Azaibi Tamin; Jennifer L. Harcourt; Natalie J. Thornburg (17 March 2020). "Aerosol and Surface Stability of SARS-CoV-2 as Compared with SARS-CoV-1". The New England Journal of Medicine. doi:10.1056/NEJMc2004973. Dicapai pada 3 April 2020.

[Thiel-3] Thiel, V., penyunting (2007). Coronaviruses: Molecular and Cellular Biology (ed. 1st). Caister Academic Press. ISBN 978-1-904455-16-5.

[4] Fehr, Anthony R.; Perlman, Stanley (2015). "Coronaviruses: An Overview of Their Replication and Pathogenesis". Coronaviruses. Methods in Molecular Biology. 1282. Clifton, New Jersey, USA. m/s. 1–23. doi:10.1007/978-1-4939-2438-7_1. ISBN 978-1-4939-2437-0. ISSN 1064-3745. PMC 4369385. PMID 25720466. SARS-CoV primarily infects epithelial cells within the lung. The virus is capable of entering macrophages and dendritic cells but only leads to an abortive infection [87,88].

[:0-5] Xing-Yi Ge; Jia-Lu Li; Xing-Lou Yang (2013). "Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor". Nature. 503 (7477): 535–538. Bibcode:2013Natur.503..535G. doi:10.1038/nature12711. PMC 5389864. PMID 24172901. Unknown parameter |displayauthors= ignored (bantuan)

[6] "Global Epidemiology of Bat Coronaviruses". Viruses. 11 (2): 174. 20 February 2019. doi:10.3390/v11020174. ISSN 1999-4915. PMC 6409556. PMID 30791586. Most notably, horseshoe bats were found to be the reservoir of SARS-like CoVs, while palm civet cats are considered to be the intermediate host for SARS-CoVs [43,44,45].

[7] "Receptor recognition and cross-species infections of SARS coronavirus". Antiviral Research. 100 (1): 246–254. October 2013. doi:10.1016/j.antiviral.2013.08.014. ISSN 0166-3542. PMC 3840050. PMID 23994189. See Figure 6.

[8] "Remembering SARS: A Deadly Puzzle and the Efforts to Solve It". Centers for Disease Control and Prevention. 11 April 2013. Diarkibkan daripada yang asal pada 1 August 2013. Dicapai pada 3 August 2013.

[9] "Coronavirus never before seen in humans is the cause of SARS". United Nations World Health Organization. 16 April 2006. Diarkibkan daripada yang asal pada 12 August 2004. Dicapai pada 5 July 2006.

[10] "Aetiology: Koch's postulates fulfilled for SARS virus". Nature. 423 (6937): 240. 2003. Bibcode:2003Natur.423..240F. doi:10.1038/423240a. PMC 7095368. PMID 12748632. Unknown parameter |displayauthors= ignored (bantuan)

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