Antazolin

Antazolin
(IUPAC) ime
	N-(4,5-dihidro-1H-imidazol-2-ilmetil)-N-(fenilmetil)anilin
Klinički podaci
Robne marke	Vasokon
AHFS/Drugs.com	Mikromedeks, detaljne potrošačke informacije
Identifikatori
CAS broj	91-75-8
ATC kod	R01AC04 R06AX05
PubChem	2200
DrugBank	DB08799
ChemSpider	2115
UNII	DHA8014SS1
KEGG	D07458
ChEMBL	CHEMBL1305
Hemijski podaci
Formula	C17H19N3
Mol. masa	265,353 g/mol
SMILES	eMolekuli & PubHem
InChI
	InChI=1S/C17H19N3/c1-3-7-15(8-4-1)13-20(14-17-18-11-12-19-17)16-9-5-2-6-10-16/h1-10H,11-14H2,(H,18,19) ; Key: REYFJDPCWQRWAA-UHFFFAOYSA-N
Farmakoinformacioni podaci
Trudnoća	?
Pravni status
Način primene	Topikalno (nazalno, kapi za oči)

Antazolin pripada prvog generaciji antihistamina koji isto tako imaju antiholinergična svojstva. On se koristi za olakšavanje nazalne kongestije i u kapima za oči, obično u kombinaciji sa nafazolinom, radi olakšavanja simptoma alergijskog konjunktivitisa.^[6]

Reference

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit
↑ Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.
↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594. edit
↑ Abelson MB, Allansmith MR, Friedlaender MH. (1980). „Effects of topically applied occular decongestant and antihistamine”. Am J Ophthalmol. 90: 254-7.

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