Share to: share facebook share twitter share wa share telegram print page

BD-1063

BD-1063
IUPAC ime
1-[2-(3,4-dichlorophenyl)ethyl]-4-methylpiperazine
Identifikatori
CAS broj150208-28-9 ДаY
ATC kodnone
PubChemCID 574780
Hemijski podaci
FormulaC13H18Cl2N2
Molarna masa273.201 g/mol
  • C2CN(C)CCN2CCc(cc1Cl)ccc1Cl

BD-1063 je antagonist sigma receptora koji je selektivan za σ1 tip. On blokira MDMA efekte u studijama na životinjama,[1] i umanjuje unos alkohola u modelima alkoholizma.[2]

Reference

  1. ^ Brammer MK, Gilmore DL, Matsumoto RR (2006). „Interactions between 3,4-methylenedioxymethamphetamine and sigma1 receptors”. European Journal of Pharmacology. 553 (1-3): 141—5. PMC 1780037 Слободан приступ. PMID 17070798. doi:10.1016/j.ejphar.2006.09.038. 
  2. ^ Sabino V, Cottone P, Zhao Y, Iyer MR, Steardo L, Steardo L, Rice KC, Conti B, Koob GF, Zorrilla EP (2009). „The sigma-receptor antagonist BD-1063 decreases ethanol intake and reinforcement in animal models of excessive drinking”. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34 (6): 1482—93. PMC 2669694 Слободан приступ. PMID 18946467. doi:10.1038/npp.2008.192. 


Molimo Vas, obratite pažnju na važno upozorenje
u vezi sa temama iz oblasti medicine (zdravlja).
Kembali kehalaman sebelumnya