GPR114

G protein spregnutih receptor 114
Identifikatori
Simboli	GPR114; PGR27
Vanjski ID	MGI: 2685955 HomoloGene: 17828 IUPHAR: GPR114 GeneCards: GPR114 Gene
Ontologija gena
Molekularna funkcija	• aktivnost G protein spregnutog receptora;
Celularna komponenta	• integralno sa ćelijskom membranom; • integralno sa membranom;
Biološki proces	• ćelijska adhezija; • signalni put G protein spregnutog receptora; • neuropeptidni signalni put;
Ortolozi

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G protein spregnuti receptor 114 je protein koji je kod ljudi kodiran GPR114 genom. On je član adhezionske GPCR familije receptora. Ti proteini imaju veliko ekstracelularni region sa varijabilnim brojem proteinskih domena spregnutih sa TM7 domenom preko regiona sličnog mucinu.^[1] ^[2]^[3]

Reference

↑ Yona, Stacey (2011). Adhesion-GPCRs. 1-200: Springer. ISBN 978-1-4419-7912-4.
↑ Fredriksson R, Lagerstrom MC, Hoglund PJ, Schioth HB (Nov 2002). „Novel human G protein-coupled receptors with long N-terminals containing GPS domains and Ser/Thr-rich regions”. FEBS Lett 531 (3): 407–14. DOI:10.1016/S0014-5793(02)03574-3. PMID 12435584.
↑ „Entrez Gene: GPR114 G protein-coupled receptor 114”.

Literatura

Strausberg RL, Feingold EA, Grouse LH, et al. (2003). „Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. DOI:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Vassilatis DK, Hohmann JG, Zeng H, et al. (2003). „The G protein-coupled receptor repertoires of human and mouse”. Proc. Natl. Acad. Sci. U.S.A. 100 (8): 4903–8. DOI:10.1073/pnas.0230374100. PMC 153653. PMID 12679517.
Clark HF, Gurney AL, Abaya E, et al. (2003). „The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment”. Genome Res. 13 (10): 2265–70. DOI:10.1101/gr.1293003. PMC 403697. PMID 12975309.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). „Complete sequencing and characterization of 21,243 full-length human cDNAs”. Nat. Genet. 36 (1): 40–5. DOI:10.1038/ng1285. PMID 14702039.
Bjarnadóttir TK, Fredriksson R, Höglund PJ, et al. (2005). „The human and mouse repertoire of the adhesion family of G-protein-coupled receptors”. Genomics 84 (1): 23–33. DOI:10.1016/j.ygeno.2003.12.004. PMID 15203201.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). „The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)”. Genome Res. 14 (10B): 2121–7. DOI:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Yona, Stacey (2011). Adhesion-GPCRs. 1-200: Springer. ISBN 978-1-4419-7912-4.

[1] Yona, Stacey (2011). Adhesion-GPCRs. 1-200: Springer. ISBN 978-1-4419-7912-4.

[pmid12435584-2] Fredriksson R, Lagerstrom MC, Hoglund PJ, Schioth HB (Nov 2002). „Novel human G protein-coupled receptors with long N-terminals containing GPS domains and Ser/Thr-rich regions”. FEBS Lett 531 (3): 407–14. DOI:10.1016/S0014-5793(02)03574-3. PMID 12435584.

[entrez-3] „Entrez Gene: GPR114 G protein-coupled receptor 114”.

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