Share to: share facebook share twitter share wa share telegram print page

BP-897

BP-897
IUPAC ime
N-[4-[4-(2-metoksifenil)piperazin-1-il]butil]naftalen-2-karboksamid
Identifikatori
CAS broj314776-92-6 ДаY
ATC kodnone
PubChemCID 3038495
ChEMBLCHEMBL25236 ДаY
Hemijski podaci
FormulaC26H31N3O2
Molarna masa417,542 g/mol
  • COc1ccccc1N3CCN(CC3)CCCCNC(=O)c4ccc2ccccc2c4

BP-897 je lek koji se koristi u naučnim istraživanjima. On deluje kao umereno selektivni parcijalni agonist dopaminski D3 receptora.[1] On je uglavnom korišćen za studiranje tretmana za kokainsku adikciju.[2][3][4][5][6][7][8]

Reference

  1. ^ Pilla M, Perachon S, Sautel F, Garrido F, Mann A, Wermuth CG, Schwartz JC, Everitt BJ, Sokoloff P (1999). „Selective inhibition of cocaine-seeking behaviour by a partial dopamine D3 receptor agonist”. Nature. 400 (6742): 371—5. PMID 10432116. doi:10.1038/22560. 
  2. ^ Beardsley PM, Sokoloff P, Balster RL, Schwartz JC (2001). „The D3R partial agonist, BP 897, attenuates the discriminative stimulus effects of cocaine and D-amphetamine and is not self-administered”. Behavioural Pharmacology. 12 (1): 1—11. PMID 11270507. 
  3. ^ Garcia-Ladona FJ, Cox BF (2003). „BP 897, a selective dopamine D3 receptor ligand with therapeutic potential for the treatment of cocaine-addiction”. CNS Drug Reviews. 9 (2): 141—58. PMID 12847556. 
  4. ^ Duarte C, Lefebvre C, Chaperon F, Hamon M, Thiébot MH (2003). „Effects of a dopamine D3 receptor ligand, BP 897, on acquisition and expression of food-, morphine-, and cocaine-induced conditioned place preference, and food-seeking behavior in rats”. Neuropsychopharmacology. 28 (11): 1903—15. PMID 12915863. doi:10.1038/sj.npp.1300276. 
  5. ^ Hsu A, Togasaki DM, Bezard E, Sokoloff P, Langston JW, Di Monte DA, Quik M (2004). „Effect of the D3 dopamine receptor partial agonist BP897 [N-[4-(4-(2-methoxyphenyl)piperazinyl)butyl]-2-naphthamide] on L-3,4-dihydroxyphenylalanine-induced dyskinesias and parkinsonism in squirrel monkeys”. The Journal of Pharmacology and Experimental Therapeutics. 311 (2): 770—7. PMID 15226382. doi:10.1124/jpet.104.071142. 
  6. ^ Gilbert JG, Newman AH, Gardner EL, Ashby CR, Heidbreder CA, Pak AC, Peng XQ, Xi ZX (2005). „Acute administration of SB-277011A, NGB 2904, or BP 897 inhibits cocaine cue-induced reinstatement of drug-seeking behavior in rats: role of dopamine D3 receptors”. Synapse (New York, N.Y.). 57 (1): 17—28. PMID 15858839. doi:10.1002/syn.20152. 
  7. ^ Spiller K, Xi ZX, Peng XQ, Newman AH, Ashby CR, Heidbreder C, Gaál J, Gardner EL (2008). „The selective dopamine D3 receptor antagonists SB-277011A and NGB 2904 and the putative partial D3 receptor agonist BP-897 attenuate methamphetamine-enhanced brain stimulation reward in rats”. Psychopharmacology. 196 (4): 533—42. PMID 17985117. doi:10.1007/s00213-007-0986-6. 
  8. ^ Hocke C, Prante O, Salama I, Hübner H, Löber S, Kuwert T, Gmeiner P (2008). „18F-Labeled FAUC 346 and BP 897 derivatives as subtype-selective potential PET radioligands for the dopamine D3 receptor”. Chemmedchem. 3 (5): 788—93. PMID 18306190. doi:10.1002/cmdc.200700327. 

Spoljašnje veze

Read other articles:

Enrico Papa

Enrico Papa Enrico Papa (Desenzano del Garda, 7 aprile 1945) è un attore italiano. Indice 1 Biografia 2 Teatro 3 Filmografia 3.1 Cinema 3.2 Televisione 4 Altri progetti 5 Collegamenti esterni Biografia Dopo gli studi liceali a Brescia si trasferisce a Parigi dove frequenta l'École Internationale de théâtre Jacques Lecoq; successivamente a Roma si iscrive alla Facoltà di Scienze politiche a La Sapienza - Università di Roma; nel contempo frequenta l'Accademia nazionale d'arte drammatica (...

 

Wudinna

Cet article est une ébauche concernant une localité australienne et l’Australie-Méridionale. Vous pouvez partager vos connaissances en l’améliorant (comment ?) selon les recommandations des projets correspondants. Wudinna Le granite de la région de Wuddina Administration Pays Australie Maire Timothy Richard Scholz Code postal SA 5652 Démographie Population 600 hab. Géographie Coordonnées 33° 02′ 00″ sud, 135° 28′ 00″ est Altitude 8...

 

Jerusalem Bible

1966 Catholic English translation of the Bible This article is about the Catholic translation. For the Jewish translation, see Koren Jerusalem Bible. The Jerusalem BibleFull nameThe Jerusalem BibleAbbreviationJB or TJBComplete Biblepublished1966Textual basisOld Testament: La Bible de Jerusalem, Masoretic text with strong Septuagint (especially in Psalms) and some Vulgate influence. New Testament: La Bible de Jérusalem, Eclectic text with high correspondence to the Nestle-Aland Novum Testamen...

Hawaii's congressional districts

U.S. House districts in the state of Hawaii Hawaii's congressional districts since 2023 The U.S. state of Hawaii is divided into two congressional districts for representation in the United States House of Representatives. Before statehood, the Territory of Hawaii was represented by a non-voting delegate. From statehood until 1963, Hawaii had one representative. From 1963 to the creation of the two districts in 1971, Hawaii was represented in the House with two representatives elected at-larg...

 

Chris Patten

British politician (born 1944) For other people with similar names, see Chris Patton (disambiguation). The Right HonourableThe Lord Patten of BarnesKG CH PCOfficial portrait, 2019Chancellor of the University of OxfordIncumbentAssumed office 20 September 2003Vice-ChancellorSir Colin LucasSir John HoodAndrew D. HamiltonLouise RichardsonIrene TraceyPreceded byThe Lord Jenkins of HillheadEuropean Commissioner for External RelationsIn office16 September 1999 – 22 November 20...

 

Radiate (Enter Shikari song)

2013 single by Enter ShikariRadiateSingle by Enter Shikarifrom the album Rat Race EP Released10 June 2013RecordedFebruary 2013GenreElectronicore, post-hardcoreLength4:32LabelAmbush RealitySongwriter(s)Chris Batten, Rou Reynolds, Rob Rolfe, Rory ClewlowProducer(s)Enter Shikari, Dan WellerEnter Shikari singles chronology The Paddington Frisk (2013) Radiate (2013) Rat Race (2013) Radiate is a single by British rock band Enter Shikari. The song was first played on Zane Lowe's BBC Radio 1 show on ...

2023 Stuttgart Surge season

American football club in Germany season 2023 Stuttgart Surge seasonGeneral managerSuni MusaHead coachJordan NeumanHome fieldGazi-Stadion auf der WaldauUniform ← 2022 Stuttgart Surge 2024 → The 2023 Stuttgart Surge season is the third season of Stuttgart Surge in the European League of Football. It is the first season with a new head coach after a winless season prior. Preseason To the end of the regular season in 2022, the team and coaching staff of the franchise w...

 

University of Saint Joseph (Connecticut)

Private Catholic university in West Hartford, Connecticut, U.S. For other schools of the same name, see Saint Joseph's College (disambiguation). This article needs additional citations for verification. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed.Find sources: University of Saint Joseph Connecticut – news · newspapers · books · scholar · JSTOR (January 2017) (Learn how ...

 

Sonic the Hedgehog 4: Episode I

2010 video game Sonic the Hedgehog 4 redirects here. For the second episode, see Sonic the Hedgehog 4: Episode II. 2010 video gameSonic the Hedgehog 4: Episode IDeveloper(s)DimpsSonic TeamPublisher(s)SegaDirector(s)Toshiyuki NagaharaProducer(s)Takashi IizukaHiroyuki KawanoDesigner(s)Yukihiro HigashiProgrammer(s)Katsuya KuramotoArtist(s)Hideaki MoriyaYuji UekawaShinji MatsuuraMichikazu TamamuraComposer(s)Jun SenoueSeriesSonic the HedgehogPlatform(s)iOS, Wii, PlayStation 3, Xbox 360, Windows, W...

Wang Ganchang

Wang Ganchang王淦昌Wang GanchangLahir28 Mei 1907Changshu, Jiangsu, Dinasti QingMeninggal10 Desember 1998(1998-12-10) (umur 91)Beijing, TiongkokAlmamaterUniversitas TsinghuaUniversitas BerlinDikenal atasMenemukan partikel hiperon minus anti-sigmaPenghargaanJINR Prize (1961)State Natural Science Award (1982)State Science and Technology Progress Award (1985)Penghargaan Dua Bom, Satu Satelit (1999)Karier ilmiahBidangFisika nuklirInstitusiUniversitas ShandongUniversitas ZhejiangInstitute o...

 

Italian Venezuelans

Venezuelan citizens of Italian descent Italian VenezuelansItalo-venezuelani (Italian)Ítalo-venezolanos (Spanish)Juan Germán Roscio was a Venezuelan lawyer and politician of Italian ancestry who was the main editor of the Venezuelan Declaration of Independence,[1] and the chief architect of the Venezuelan Constitution of 1811Total populationc. 30,000 (by birth)[2] c. 5,000,000 (by ancestry, about 16% of the total Venezuelan population)[3][4&#...

 

Namakkal Fort

For other places with the same name, see Namakkal (disambiguation). Namakkal FortPart of Tamil NaduNamakkal, Tamil Nadu, India Namakkal FortNamakkal FortCoordinates11°14′00″N 78°10′00″E / 11.233333°N 78.166667°E / 11.233333; 78.166667TypeFortsSite informationControlled byDepartment of Archaeology Namakkal Fort is a historic fort present in Namakkal in Namakkal district in the South Indian state of Tamil Nadu. The fort was built during the reign of Thir...

SMA Negeri 1 Sanana

Artikel ini sebatang kara, artinya tidak ada artikel lain yang memiliki pranala balik ke halaman ini.Bantulah menambah pranala ke artikel ini dari artikel yang berhubungan atau coba peralatan pencari pranala.Tag ini diberikan pada April 2016. SMA Negeri 1 SananaInformasiJenisNegeriAkreditasiA (89,00) [1]Nomor Pokok Sekolah Nasional60200544 [2]Kepala SekolahDra. Sultiya Umasangaji (sekarang)Jumlah kelas8 kelas setiap tingkat (RSBI)Jurusan atau peminatanIPA dan IPSRent...

 

Masonic myths

Myths present in masonic rites and ranks Part of a series onFreemasonry Overview Grand Lodge Masonic lodge Masonic lodge officers Grand Master Prince Hall Freemasonry Regular Masonic jurisdiction Anglo-American Freemasonry Continental Freemasonry History History of Freemasonry Liberté chérie Masonic manuscripts Masonic bodies Masonic Masonic bodies York Rite Order of Mark Master Masons Holy Royal Arch Royal Arch Masonry Cryptic Masonry Knights Templar Red Cross of Constantine Scottish Rite ...

 

Bigg Boss Kannada

Indian reality television series Bigg Boss KannadaBigg Boss Season 10 Poster with host SudeepaPresented bySudeepaCountry of originIndiaOriginal languageKannadaNo. of seasons10No. of episodes1090 (as of 5 September 2023)ProductionProduction locationsLonavala(Season 1 & 2)Bengaluru(Season 3 - present)Camera setupMulti-CameraProduction companyEndemol IndiaOriginal releaseNetworkETV Kannada(Season 1)Star Suvarna(Season 2)Colors Kannada(Season 3,4,7,8,9 &10)Colors Super(Season 5 & 6)Re...

Dies (mythology)

Personification of the day in Roman mythology DiesPersonification of dayHemera/Dies (1881) by William-Adolphe BouguereauPersonal informationParentsChaos and CaligoSiblingsNox, Erebus, and AetherConsortAether, CaelusChildrenTerra, Caelus, MareEquivalentsGreek equivalentHemera In Roman mythology, Dies /ˈdaɪ.iːz/[1] (Latin diēs day) was the personification of day. She was the daughter of Chaos and Caligo (Mist), and the counterpart of the Greek goddess Hemera. Family According to the...

 

Wombwell Central railway station

Disused railway station in South Yorkshire, England Wombwell CentralSite of the former station (2007)General informationLocationWombwell, BarnsleyEnglandCoordinates53°31′22″N 1°23′36″W / 53.5229°N 1.3932°W / 53.5229; -1.3932Grid referenceSE403030Platforms2Other informationStatusDisusedHistoryOriginal companySouth Yorkshire RailwayPre-groupingGreat Central RailwayPost-groupingLondon and North Eastern RailwayKey dates1851opened29 June 1959closed for passenger...

 

Sprinter New Generation

Class of Dutch electric multiple units This article needs additional citations for verification. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed.Find sources: Sprinter New Generation – news · newspapers · books · scholar · JSTOR (May 2022) (Learn how and when to remove this template message) You can help expand this article with text translated from the corresponding article in ...

Kroll Opera House

Former opera house in Berlin, Germany This article needs additional citations for verification. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed.Find sources: Kroll Opera House – news · newspapers · books · scholar · JSTOR (January 2021) (Learn how and when to remove this template message) 52°31′07″N 13°22′14″E / 52.51861°N 13.37056°E / 52.5186...

 

Phacellodomus maculipectus

  Espinero de pecho manchado Espinero de pecho manchado (Phacellodomus maculipectus) en Animas, Salta, Argentina.Estado de conservaciónPreocupación menor (UICN 3.1)[1]​TaxonomíaReino: AnimaliaFilo: ChordataClase: AvesOrden: PasseriformesFamilia: FurnariidaeSubfamilia: FurnariinaeTribu: SynallaxiniGénero: PhacellodomusEspecie: P. maculipectusCabanis, 1883[2]​Distribución Distribución geográfica del espinero de pecho manchado.Sinonimia Phacellodomus striaticollis ma...

 
Kembali kehalaman sebelumnya